2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Melanocortin Receptor
  5. Melanocortin Receptor Isoform
  6. Melanocortin Receptor Inhibitor

Melanocortin Receptor Inhibitor

Melanocortin Receptor Inhibitors (24):

Cat. No. Product Name Effect Purity
  • HY-11029
    SNT-207707
    		Inhibitor 99.51%
    SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor.
  • HY-P3561A
    Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)
    		Inhibitor
    Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake.
  • HY-N12267
    N,N′-Diferuloylputrescine
    		Inhibitor
    N,N′-Diferuloylputrescine ((E/Z)-Terrestribisamide) is a inhibitor of pigmentation with 57% reduction. N,N′-Diferuloylputrescine significantly reduces the protein level of MITF. N,N′-Diferuloylputrescine has strong antioxidant activities as radical scavengers against reactive oxygen species.
  • HY-P3981
    Defensin NP-3A
    		Inhibitor
    Defensin NP-3A (NP-3A; Corticostatin 1) is a human granulocyte peptide, with anti-ACTH activity. Defensins are antimicrobial peptides with and cytotoxic activity.
  • HY-RS08210
    Mc4r Mouse Pre-designed siRNA Set A
    		Inhibitor

    Mc4r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mc4r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08200
    MC1R Human Pre-designed siRNA Set A
    		Inhibitor

    MC1R Human Pre-designed siRNA Set A contains three designed siRNAs for MC1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08212
    MC5R Human Pre-designed siRNA Set A
    		Inhibitor

    MC5R Human Pre-designed siRNA Set A contains three designed siRNAs for MC5R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08213
    Mc5r Mouse Pre-designed siRNA Set A
    		Inhibitor

    Mc5r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mc5r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08209
    MC4R Human Pre-designed siRNA Set A
    		Inhibitor

    MC4R Human Pre-designed siRNA Set A contains three designed siRNAs for MC4R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08205
    Mc2r Rat Pre-designed siRNA Set A
    		Inhibitor

    Mc2r Rat Pre-designed siRNA Set A contains three designed siRNAs for Mc2r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08206
    MC3R Human Pre-designed siRNA Set A
    		Inhibitor

    MC3R Human Pre-designed siRNA Set A contains three designed siRNAs for MC3R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08202
    MC1R Rat Pre-designed siRNA Set A
    		Inhibitor

    MC1R Rat Pre-designed siRNA Set A contains three designed siRNAs for MC1R gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-134046
    (-)-Isodocarpin
    		Inhibitor
    (-)-Isodocarpin (Isodocarpin), a diterpenoid, is a potent melanogenesis inhibitor with an IC50 of 0.19 μM in B16 4A5 cells. (-)-Isodocarpin inhibits the expression of tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA.
  • HY-P10265
    Melanostatin, frog
    		Inhibitor
    Melanostatin, frog is an inhibitor for α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM.
  • HY-155189
    IIIM-8
    		Inhibitor
    IIIM-8 is a melanogenesis inhibitor. IIIM-8 inhibits pigment production both in vitro and in vivo without incurring any cytotoxicity in Human Adult Epidermal Melanocytes (HAEM). IIIM-8 can be used for hyperpigmentation disorders research.
  • HY-RS08204
    Mc2r Mouse Pre-designed siRNA Set A
    		Inhibitor

    Mc2r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mc2r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-N7587
    Chlorophorin
    		Inhibitor
    Chlorophorin is a inhibitor of Melanocortin Receptor. Chlorophorin reduces tyrosinase activity and inhibits a-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells.
  • HY-RS08208
    Mc3r Rat Pre-designed siRNA Set A
    		Inhibitor

    Mc3r Rat Pre-designed siRNA Set A contains three designed siRNAs for Mc3r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08201
    Mc1r Mouse Pre-designed siRNA Set A
    		Inhibitor

    Mc1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mc1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08214
    Mc5r Rat Pre-designed siRNA Set A
    		Inhibitor

    Mc5r Rat Pre-designed siRNA Set A contains three designed siRNAs for Mc5r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.